What is PGS and how is it Helpful?

The main advantage of PGS (Preimplantation Genetic Diagnosis for single gene disease) is that, with this technology, we are able to improve reproductive success by carefully selecting the embryos that are chromosomally normal among all the other embryos of the patient.

PGS is normally performed on women who are of advanced maternal age, or on those who have had many miscarriages or the embryo has failed to implant itself on to the uterus. Infertility can also occur due to the male factors like low sperm count.

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In PGS, 24 chromosomes are analysed so as to negate the possibility of having the wrong number of chromosomes in a cell before it is implanted. This is known as embryonic aneuploidy. Array Comparative Genomic Hybridization (aCGH) is when the chromosomes are analysed so it terminates the possibility of any genetic disorder. By using this method, there is a higher percentage of informed embryos by using only one embryonic cell. By using PGS, the chances of ongoing pregnancy rates are doubled and the results are also higher than that of FISH.

PGS result are obtained in 4 steps:

  • Biopsy – when one embryonic cell is biopsied from each embryo.
  • Tubing – when each cell is placed in specific tubes so as to avoid any kind of DNA contamination.
  • Transportation – these tubes are then shipped with specific coolers that is provided in the kit.
  • Result – in which the embryonic cell is analysed and it also specifies the number of normal embryos that can be transferred.

For more information regarding our PGS services, visit our website, http://www.iviomics.co.in/. Facebook page https://www.facebook.com/iviomics, or to contact, mail us at info.india@iviomics.com or call us at +91 11 6651 7800 for further assistance.

 

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Who Needs IVF?

IVF (In- Vitro Fertilization) is opted by many couples over the world that are unable to conceive a baby normally and thus seek assisted reproduction. Couples who have fallopian tube damage, endometriosis (endometriosis occurs when endometrial cells enter the pelvic cavity through a back flow of blood during the menstrual cycle and attach to internal organs), recurrent pregnancy loss related to chromosomal abnormalities, infertility due to age, genetic disease such as cystic fibrosis etc. often opt for IVF. Couples also seek IVF due to male related problems like low sperm count or any other irregularities.

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With our help at Iviomics, you can conceive healthy babies with our cutting edge, leading technology. Iviomics is the global leader in genetic diagnostics and pioneer in the field of reproductive genetics. We provide services to IVF clinics and Obstetricians across the world and is renowned for its extensive experience in molecular genetic diagnostics. We offer varied services that cater to your needs, like PGS (Preimplantation Genetic Screening) for chromosomal abnormalities, PGD (Preimplantation Genetic Diagnosis) for single gene diseases, ERA (Endometrial Receptivity Array) for identification of personalized window of implantation, NACE (Non-invasive Analysis for Chromosomal Examination) for non-invasive prenatal assessment of chromosomal abnormalities in fetus, POC (Products of Conception analysis by array CGH) for finding the etiology of unexplained abortions and CGT (Compatible Genetic Test) which helps to determine the risk of having a child with a genetic disease.

 

For more information regarding our services, visit our website, http://www.iviomics.co.in

Facebook page: https://www.facebook.com/iviomics

or to contact, mail us at info.india@iviomics.com or call us at +91 11 6651 7800.

 

What is IVF and how it helps?

At this very moment, there are more than a million infertile couples in India trying for IVF (in vitro fertilization); also known as ‘test tube’ baby. Over the years, this has become the magic word for infertile couples desperately desirous of a child. Through this technology, which is a boon to mankind, many who had no chance of having their own child, are now proud parents.

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In a normal pregnancy a male sperm penetrates a woman’s egg and fertilizes it inside her body after ovulation – when a mature egg has been released from the ovaries. The fertilized egg (now an embryo) then attaches itself to the wall of the uterus (womb) and begins developing into a baby. This is known as natural conception. However, some women are unable to become pregnant through natural or unassisted conception due to various reasons and thus have to undergo fertility treatment to become pregnant. The procedure involves fertilizing an egg outside the body, in a laboratory dish, and then implanting it in a woman’s uterus.

With our help at Iviomics, you can conceive healthy babies with our cutting edge, innovative technology. Iviomics is the global leader in genetic diagnostics and pioneer in the field of reproductive genetics. We provide services to In-Vitro Fertilization (IVF) clinics and Obstetricians across the world and are renowned for our extensive experience in molecular genetic diagnostics. At Iviomics, we offer services like PGS (Preimplantation Genetic Screening) for chromosomal abnormalities, PGD (Preimplantation Genetic Diagnosis) for single gene diseases, ERA (Endometrial Receptivity Array) for identification of personalized window of implantation, NACE (Non-invasive Analysis for Chromosomal Examination) for non-invasive prenatal assessment of chromosomal abnormalities in fetus, POC (Products of Conception analysis by array CGH) for finding the etiology of unexplained abortions and CGT (Compatible Genetic Test) which helps to determine the risk of having a child with a genetic disease.

For more information regarding our services, visit our website, http://www.iviomics.co.in/.

Facebook page https://www.facebook.com/iviomics, or to contact, mail us at info.india@iviomics.com or call us at +91 11 6651 7800.

Endometrial Receptivity Array (ERA): New Technology!

IVIOMICS, a pioneer in reproductive genetics, brings to you a new revolutionary technology that can increase the chances of pregnancy in patients with repeated implantation failure. Endometrial Receptivity Array (ERA) can determine the best time for implantation of the embryo. This test has been developed after 3000 clinical trials that have been conducted over 10 years. ERA determines how receptive a woman’s uterus is at a particular stage in her menstrual cycle by analyzing the fertility factor of 238 genes than just relying on the appearance of the endometrium.

 

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“The best benefits of ERA are achieved for patients who have failed an implantation with apparently good looking embryos in a physically normal looking uterine cavity,” explains Dr. Richa Jagtap, Clinical Director & Consultant, Nova IVI Fertility, Chembur, Mumbai. “Each failure is difficult to digest for the patient as well as to the treating physician. Hence rather than blindly repeating the treatment for the patient and wasting good quality embryos, it makes better sense to pinpoint a time frame which is best for an embryo to implant.”

 

Ordinary technology is still unable to identify the exact ‘window of implantation’, that is, the time period in which the uterus is ready for embryo transfer. “Until now, the time for transfer of an embryo was determined by the diagnostic imaging (USG) and sometimes with help of hormone check. As is expected, both of the above can give a good picture and still the uterus may be non-receptive. To overcome this we take help of the ERA test”, says Dr. Jagtap. The results obtained by the ERA are accurate and consistent in different cycles of the same patient.

 

According to Dr Rajni Khajuria – Laboratory Head, Iviomics India, “previously, doctors had no choice but to repeat the IVF cycles till there was a success or otherwise. Now, after ERA, timely implantation is possible which increases the success rate of pregnancy and reduces the time that patients have to wait to achieve a pregnancy.”

 

For more information regarding our services, visit our website, http://www.iviomics.co.in/.

Facebook page https://www.facebook.com/iviomics, or to contact, mail us at info.india@iviomics.com or call us at +91 11 6651 7800.

Introducing Iviomics:

IVIOMICS is the global leader in genetic diagnostics and pioneer in the field of reproductive genetics. IVIOMICS provides services to In-Vitro Fertilization (IVF) clinics and Obstetricians across the world and is renowned for its extensive experience in molecular genetic diagnostics. IVIOMICS currently performs the highest number of Pre-implantation Genetic Diagnostic (including PGD and PGS) procedures in Europe.

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Services offered by IVIOMICS include PGS (Preimplantation Genetic Screening) for chromosomal abnormalities, PGD (Preimplantation Genetic Diagnosis) for single gene diseases, ERA (Endometrial Receptivity Array) for identification of personalized window of implantation, NACE (Non-invasive Analysis for Chromosomal Examination) for non-invasive prenatal assessment of chromosomal abnormalities in foetus, POC (Products of Conception analysis by array CGH) for finding the etiology of unexplained abortions and CGT (Compatible Genetic Test) which helps to determine the risk of having a child with a genetic disease. IVIOMICS also offers experienced genetic counseling through phone consultations.
 

All IVIOMICS services are available and can be performed 24 hours a day, 7 days a week. The lab’s international branches are located in New Delhi (India), Los Angeles and Miami (USA) and Milan (Italy) with headquarters situated in Valencia (Spain).

 

For more information on the services provided, contact us at info.india@iviomics.com or call us, +91 11 6651 7800. Visit and like our Facebook page- https://www.facebook.com/iviomics to know more.